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William S. Poole was appointed to our board of directors on April 28 2005. He was formerly a member of Arius’ Commercial Advisory Board. Mr. Poole has extensive experience in the bio-pharmaceutical and medical device industries for over thirty years. From 1972 to early 1996 Mr. Poole worked for Lederle Laboratories a Division of American Cyanamid Company. During his 24-year career at Cyanamid Mr. Poole held positions of increasing responsibility and held the position of World-Wide Division President of the Medical Device Division when Wyeth acquired Cyanamid in 1995. After a brief stint as President of Fisons Pharmaceuticals which was acquired by Rhone Poulenc-Rorer Mr. Poole went on to become President North American Pharmaceuticals of Novo Nordisk Pharmaceuticals where he served from 1997 to 2000. From 2001 to 2003 he served as President of Biovail Pharmaceuticals. In both of these companies Mr. Poole was instrumental in aggressively growing revenue building a solid management team and dramatically improving profitability. As President of these firms Mr. Poole had total P&L responsibility and directly oversaw vice presidents in charge of manufacturing research & development sales legal marketing finance regulatory and human resources functions. Since his departure from Biovail Mr. Poole has acted as an independent consultant to the pharmaceutical industry. Mr. Poole graduated from Boston University in 1972 with a B.A. Psychology. | 