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Susan Sumner, PhD, has more than 15 years of experience in mechanistic-based research, specializing in the areas of metabolism and metabolomics. Dr. Sumner has served as a principal investigator and GLP study director, conducting studies to evaluate the blood pharmacokinetics, absorption, metabolism, distribution, and toxicity of compounds. Her early career activities at the CIIT Centers for Health Research (1989-2002) led to the development of an NMR approach to characterize and quantify metabolites in urine from rodents and humans following controlled exposure to carbon-13-labeled compounds. She is experienced with the development of IRB protocols for volunteer exposures to environmental and pharmaceutical agents, providing guidance in study design and sample collection for compliance with analytical measurements. Dr. Sumner joined RTI in 2004 as a senior metabolism scientist, where she immediately integrated an RTI-wide metabolomics effort and developed a scientific plan to study mechanisms of idiosyncratic drug-induced liver injury. | 