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Timothy Schacker, M.D. is an Associate Professor of Medicine and the Associate Division Director. He joined the Division in September of 1996. Dr. Schacker received his M.D. from the University of Minnesota in 1986 and completed a residency in Internal Medicine at the Oregon Health Sciences University. He completed a fellowship in Infectious Diseases at the University of Washington and joined the UW faculty in 1993. Dr. Schacker has developed a translational research program focused on HIV transmission and pathogenesis. Areas of interest include factors that increase the likelihood and efficiency of HIV transmission and T cell homeostasis in HIV-1 infected persons.
Selected Publications:
Schacker T, Coombs RW, Collier AC, Zeh JE, Fox I, Alam J, Nelson K, Eggert E, Corey L. The effects of high-dose recombinant soluble CD4 on human immunodeficiency virus type 1 viremia. J Infect Dis 1994; 169:37-40.
Schacker T, Collier AC, Hughes J, Shea T, Corey L. Clinical and epidemiologic features of primary HIV infection. Ann Intern Med 1996; 125:257-64.
Haase AT, Schacker TW. Potential for the transmission of HIV-1 despite highly active antiretroviral therapy. N Engl J Med 1998; 339:1846-8.
Schacker TW, Hughes JP, Shea T, Coombs RW, Corey L. Biological and virologic characteristics of primary HIV infection. Ann Intern Med 1998; 128:613-20.
Schacker T, Ryncarz AJ, Goddard J, Diem K, Shaughnessy M, Corey L. Frequent recovery of HIV-1 from genital herpes simplex virus lesions in HIV-1-infected men. Jama 1998; 280:61-6.
Schacker T, Little S, Connick E, Gebhard-Mitchell K, Zhang ZQ, Krieger J, Pryor J, Havlir D, Wong JK, Richman D, Corey L, Haase AT. Rapid accumulation of human immunodeficiency virus (HIV) in lymphatic tissue reservoirs during acute and early HIV infection: implications for timing of antiretroviral therapy. J Infect Dis 2000; 181:354-7.
Schacker T, Little S, Connick E, Gebhard K, Zhang ZQ, Krieger J, Pryor J, Havlir D, Wong JK, Schooley RT, Richman D, Corey L, Haase AT. Productive infection of T cells in lymphoid tissues during primary and early human immunodeficiency virus infection. J Infect Dis 2001; 183:555-62
Schacker, T, Nguyen, P, Gatell, J., Reilly, C., Martinez, E., Horban, A., Bakawska, E., Leeuwen, R., Wolinsky, S., Haase, A., Murphy, R., Persistent Abnormalities in Lymphoid Tissues of HIV-Infected Persons Successfully Treated With Anti-Retroviral Therapy. J Infect Dis 2002; 186:1042-7.
Schacker, TW, Nguyen, PL, Beilman, GJ, Wolinsky, S., Larson, M., Reilly, C., Haase, AT. Collagen deposition in HIV-1 infected lymphatic tissues and T-cell homeostasis. Journal of Clinical Investigation; 110:1133-1139. |
