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Nicholas J. Simon joined the Board of Directors in April 2006. He has been a managing director of Clarus Ventures Inc. LLC a life sciences focused venture capital firm that he co-founded in 2005. He has served as a general partner of MPM BioVentures III since October 2001. He has more than 26 years of industry and investment experience in biotechnology. From 2000 to July 2001 he was chief executive officer founder and a director of Collabra Pharma Inc. a pharmaceutical development company. From 1989 to 2000 Mr. Simon served in various management positions at Genentech Inc. including vice president of business and corporate development. Mr. Simon currently serves on the boards of directors of Barrier Therapeutics Inc. and CoTherix Inc. both public biotechnology companies. In addition he is a director of ARYx Therapeutics Inc. NeoSil Incorporated QuatRx Pharmaceuticals Co. and Verus Pharmaceuticals Inc. which are private biotechnology companies. He also is on the advisory council at the Gladstone Institute a private not-for-profit research institute affiliated with the University of California San Francisco. Mr. Simon received a B.S. degree in microbiology from the University of Maryland and an M.B.A. in marketing from Loyola University. | 