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Nancy A. Simonian, M.D. joined the ArQule Board of Directors in May 2006. Dr. Simonian is currently Chief Medical Officer and Senior Vice President of Clinical, Medical and Regulatory Affairs at Millennium Pharmaceuticals, where she has worked since 2001. From 1995 to 2001, Dr. Simonian was at Biogen where she was the Vice President of Medical Research responsible for the development of Avonex, Tysabri and multiple gene therapy clinical development programs. Prior to joining industry, Dr. Simonian was on the faculty of Massachusetts General Hospital and Harvard Medical School as an Assistant Professor of neurology and was engaged in both basic science and clinical research related to neurodegenerative diseases. Dr. Simonian graduated from Princeton University, received her M.D. from the University of Pennsylvania Medical School, and completed her internship in medicine and residency in neurology at the Massachusetts General Hospital. | 