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Dr. Jaffe has been a consultant to the health care industry since April 1994. From August 1988 until March 1994 he was president of the RW Johnson Pharmaceutical Research Institute, where he was responsible for the global research and development activities of a group of Johnson & Johnson companies, including Ortho and McNeil Pharmaceutical, Ortho Biotech and Cilag. Prior to joining Johnson & Johnson, Dr. Jaffe held several senior positions in drug development at Merck & Co., Inc. He also serves as a Director of Celltech Group, plc, a biopharmaceutical company, Vernalis Group, plc, a biopharmaceutical company focusing on neurological diseases, and Allos Therapeutics, Inc. (formerly Hemotech Sciences), a biopharmaceutical company. | 