Dr. Wolff’s primary area of concentration is infectious diseases with substantial experience in all phases of clinical vaccine development. Among his achievements in this area are the design and analysis of Phase III clinical trials that were pivotal in obtaining FDA licensure.

In 1994, Dr. Wolff joined EMMES as Co-Principal Investigator on an AIDS vaccine evaluation study. Later, he became the Principal Investigator for a clinical and epidemiology contract in infectious disease that involved large, pivotal Phase III studies in influenza and genital herpes, and Phase I, II, III and IV studies of syphilis, vaccinia, cytomegalovirus, Lyme disease, herpes labialis, pneumococcal disease, vaccinia, pediatric combination vaccines, malaria and chronic fatigue syndrome. Dr. Wolff’s team also provided technical reviews for the International Collaboration in Infectious Diseases Research.

Dr. Wolff earned his Ph.D. in mathematics at the State University of New York at Stony Brook. Prior to joining EMMES, his professional experience included a joint faculty appointment at the Johns Hopkins School of Hygiene and Public Health Departments of International Health and Biostatistics. In this appointment he was the Co-Principal Investigator and statistician for a pivotal Phase III trial of a Haemophilus Influenzae vaccine, statistician for epidemiologic studies of diarrheal diseases and provided on-site consultation to clinical studies in Indonesia, Costa Rica, Peru and Guatemala. Prior to his work at Hopkins, he was the lead statistician for the Neuroclinical Trials Center at the University of Virginia.