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Jay S. Yadav, M.D. is a co-founder and has served as Chairman of our board of directors since our inception in November 2000. From our inception to October 2006, Dr. Yadav served as one of our consultants. In May 2006, Dr. Yadav was appointed as our Acting Chief Executive Officer and became an employee and our Chief Executive Officer in October 2006. From 1998 to August 2006, Dr. Yadav held various staff positions at the Cleveland Clinic Foundation, or CCF, including the Ferchill Distinguished Chair, Chairman of the Center for Medical Innovation as well as Director of Vascular Intervention. From 1997 to 1999, Dr. Yadav was the founder and Chairman of the Board of Directors of AngioGuard, Inc., developer of the first filter for emboli prevention during interventional and surgical procedures, which was acquired by Johnson & Johnson in 1998. Dr. Yadav serves on the board of directors of several private medical device and technology companies. Dr. Yadav holds a B.S. from Yale University and an M.D. from West Virginia University Medical School. Dr. Yadav’s post-graduate medical training was performed at Duke University and The University of Alabama at Birmingham. | 