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Jamie Topper is a member of the Metastatix Board of Directors. Dr. Topper is also a General Partner at Frazier Healthcare Ventures, the lead investor in Metastatix B series.Dr Topper joined Frazier Healthcare in 2003 as a Venture Partner and became a General Partner in 2005. Since joining Frazier Healthcare, Dr. Topper has led several biopharma investments. Dr. Topper currently serves on the boards of Amicus Therapeutics, Arête Therapeutics, Calistoga Pharmaceuticals, Intradigm Corporation, La Jolla Pharmaceuticals (LJPC), MacuSight Inc., Zelos Therapeutics, Inc., and is an observer on the boards of Point Biomedical and Portola Pharmaceuticals. Dr. Topper is also an advisory board member to the Harvard-Partners Center for Genetics and Genomics.Prior to joining Frazier Healthcare, he served as head of the cardiovascular research and development franchise at Millennium Pharmaceuticals and ran Millennium San Francisco (formerly COR Therapeutics). Prior to the merger of COR and Millennium, Dr. Topper served as the Vice President of Biology at COR and was responsible for managing all of its research activities. He served on the faculties of Stanford Medical School and Harvard Medical School prior to joining COR, where he functioned as a clinician, instructor and basic investigator. Dr. Topper received his M.D. and Ph.D. (in Biophysics) from Stanford University School of Medicine in 1991 under the auspices of the Medical Scientist Training Program. He completed his postgraduate training in Internal Medicine and Cardiovascular Disease at the Brigham and Women's Hospital in Boston and is board certified in both disciplines. After completing a research fellowship in the Vascular Research Division in the department of Pathology at the Brigham and Women's hospital, he joined the faculty of Harvard Medical School from 1997 to 1998, and subsequently Stanford University as an Assistant Professor of Medicine (Cardiovascular) in July 1998. He has authored over 50 publications and was the recipient of a Howard Hughes Scholars Award while on the faculty at Stanford University. He continues to hold an appointment as a Clinical Assistant Professor of Medicine at Stanford University and as a Cardiology Consultant to the Palo Alto Veterans Administration Hospital. | 