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James M. Gower has been our Chairman of the Board and Chief Executive Officer since October 2001. Mr. Gower joined us as our President, Chief Executive Officer and as a member of our board of directors in January 1997. From 1992 to March 1996 Mr. Gower was President and Chief Executive Officer of Tularik, Inc., a biotechnology company developing small-molecule drugs regulating gene expression. Prior to Tularik, Mr. Gower spent ten years at Genentech, Inc., where he most recently served as Senior Vice President. During his ten years at Genentech, Mr. Gower was responsible for business development and sales and marketing functions. In addition, he established and managed Genentech’s foreign operations in Canada and Japan and served as president of Genentech Development Corporation. He previously held various positions with American Hospital Supply Corporation. In addition to his role at Rigel, Mr. Gower serves on the board of directors of Cell Genesys, Inc. He holds an M.B.A from the University of Tennessee. | 